biodegradable medical raw material Poly(DL-lactide-co-glycolide) (PDLGA for implant) (medical level)

                          PDLGA Specification

Chemical Structure:

Instructions:

Poly(DL-lactide-co-glycolide) (PDLGA) is produced from lactic acid and glycolic acid. It is non-toxic and has excellent biodegradability, biocompatibility, film or capsule forming ability. PDLGA is widely used in pharmaceutical, medical engineering materials and modern industrial fields. In the United States, PDLGA has been approved by the FDA and is formally included in the United States pharmacopoeia as pharmaceutical materials.

PDLGA is a amorphous polymer. The glass transition temperature (Tg) of PDLGA is 40 - 60 °C. It has been widely used in medical surgical sutures, anti-adhesion membrane, tissue engineering scaffolds and so on. The degradation rate of PDLGA increases with the increase of GA proportion. Different types of PDLGA can be produced using differentmonomer ratio . For example, PDLGA 75:25 indicates that the polymer consists of 75% DL-lactic acid and 25% glycolic acid.

The degradation products of PDLGA are lactic acid and glycolic acid, so they do not have toxic side effects when used as the pharmaceutical and biological materials. PDLGA has been widely used in biomedical fields, such as medical anti-adhesion membrane, skin graft, stitched wound, injectable microcapsules, microspheres, implants, scaffolds for tissue engineering.